AC3573

SKU: orb3033069

Description

AC3573 (AC-3573) is a potent, specific small molecule inhibitor of HER3.AC3573 abrogates HER2–HER3 signalling in cells and is more specific for HER3, inhibits NRG (heregulin)-induced HER3 phosphorylation with IC50 of 10 uM, abrogates the formation of the active HER2-HER3 heterodimer, inhibits oncogenic downstream signalling in SK-BR-3 breast cancer cells.

Key Properties

• MW: 365.411
• Purity: >98%
• Formula: C₁₈H₁₅N₅O₂S

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only