Ac2-26 ammonium

• Catalog Number: orb1944595
• Category: Small Molecules
• Description: Ac2-26 ammonium is an Annexin-A1 (AnxA1) N-terminal derived peptide with anti-inflammatory activity and alleviates liver ischemia-reperfusion injury in mice by regulating IL-22/IL-22R1/STAT3 signaling and eNOS pathways.
• Purity: 95.58%
• MW: 3089.43 (free base)
• Formula: C₁₄₁H₂₁₀N₃₂O₄₄S.xNH₃
• Biological Activity: Ac2-26 ammonium, an N-terminal peptide of annexin 1, exhibits anti-inflammatory properties, reduces IKKβ protein levels in lysosomes via chaperone-mediated autophagy (CMA), improves lung ischemia-reperfusion injury outcomes, and mitigates airway inflammation and hyperresponsiveness in an asthma rat model [1] [2] [3] [4].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.