Ac-YVAD-CHO

SKU: orb1987432

Description

Ac-YVAD-CHO is a potent, selective caspase-1 (ICE) inhibitor that blocks IL-1β maturation, exhibits anti-inflammatory effects, and inhibits cancer cell growth. Research applications include studying pyroptosis and neuroinflammation, with in vivo studies demonstrating its neuroprotective role in models of striatal apoptosis.

Research Area

Cell Biology, Immunology & Inflammation, Protein Biochemistry

Key Properties

• Target: Caspase,Interleukin,Apoptosis
• CAS Number: 143313-51-3
• MW: 492.52
• Purity: 96.49% (May vary between batches)
• Formula: C₂₃H₃₂N₄O₈
• SMILES: [C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC(C)=O)=O)(C(N[C@H](C(N[C@@H](CC(O)=O)C=O)=O)C)=O)C(C)C

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AcYVADCHO, Ac-YVAD-CHO, Ac YVAD CHO, caspase-1, Apoptosis, L 709049, L709049, L-709049

Compound Identifiers

PubChem CID

5311139