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Ac-Trp-Glu-His-Asp-Aldehyde

SKU: orb1980842

Description

Ac-Trp-Glu-His-Asp-aldehyde is a highly potent and selective caspase-1 inhibitor with a K_i of 56 pM. This cell-permeable tetrapeptide aldehyde is widely used in biochemical and cellular research to study inflammasome activation and pyroptosis in both in vitro and in vivo models.

Research Area

Cell Biology, Protein Biochemistry

Images & Validation

Key Properties

TargetCaspase
CAS Number189275-71-6
MW611.6
FormulaC28H33N7O9
SMILESCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(O)=O)C=O

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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