Ac-Trp-Glu-His-Asp-Aldehyde

SKU: orb1980842

Description

Ac-Trp-Glu-His-Asp-aldehyde is a highly potent and selective caspase-1 inhibitor with a K_i of 56 pM. This cell-permeable tetrapeptide aldehyde is widely used in biochemical and cellular research to study inflammasome activation and pyroptosis in both in vitro and in vivo models.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• Target: Caspase
• CAS Number: 189275-71-6
• MW: 611.6
• Formula: C₂₈H₃₃N₇O₉
• SMILES: CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(O)=O)C=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5311140