Ac-Ile-Glu-Thr-Asp-pNA

SKU: orb1984620

Description

Ac-Ile-Glu-Thr-Asp-pNA is a colorimetric substrate for caspase-8, which cleaves the IETD sequence to release p-nitroaniline detectable at 405 nm. This substrate is widely used in vitro to measure caspase-8 activity in apoptosis research for both cell-based and biochemical assays.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• Target: Caspase
• CAS Number: 219138-21-3
• MW: 638.62
• Formula: C₂₇H₃₈N₆O₁₂
• SMILES: CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25108782