AC-261066

SKU: orb1707725

Description

AC-261066 is a potent and selective RARβ2 agonist with an oral bioavailability and a pEC50 of 8.0. This small molecule is utilized in research to investigate retinoid receptor signaling in models of neurodegeneration, cancer, and metabolic disorders, both in vitro and in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 870773-76-5
• MW: 353.41
• Purity: 99.64% (May vary between batches)
• Formula: C₁₇H₂₀FNO₄S
• SMILES: CCCCOCCOc1nc(sc1C)-c1ccc(C(O)=O)c(F)c1
• Target: Retinoid Receptor
• Solubility: DMSO:40 mg/mL (113.18 mM)

Bioactivity

• Target IC50:
  RARβ2:8.0 （pEC50）

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RARβ2, RARβ, RetinoidReceptor, Retinoid Receptor, AC 261066, AC261066, AC-261066

Compound Identifiers

PubChem CID

11530459