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ABS-752

SKU: orb3136894

Description

ABS-752 is an effective and orally active molecular glue degrader targeting GSPT1 and NEK7. It exhibits cytotoxic properties and reduces the protein expression of GSPT1, SALL4, and NEK7. ABS-752 possesses anticancer activity and shows potential for research in hepatocellular carcinoma.

Research Area

Cancer Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2761170-84-5
MW291.28
FormulaC14H14FN3O3
SMILESO=C1NC(=O)C(N2C(=O)C3=CC(F)=C(C=C3C2)CN)CC1
TargetMAPK,Molecular Glues,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information