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ABM-14

SKU: orb1691343

Description

ARCC-4 is a PROTAC molecule that induces androgen receptor (AR) degradation by conjugating the AR ligand ABM-14 to a VHL ligand. This bifunctional degrader is a valuable chemical tool for studying AR function in prostate cancer research, applicable in both cellular and in vivo models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1973408-76-2
MW481.49
FormulaC25H18F3N3O2S
SMILESCC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(cc1)-c1ccc(O)cc1
TargetOthers,Ligands for Target Protein for PROTAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information