ABD957

SKU: orb1744133

Description

ABD957 is a potent, selective covalent inhibitor of the ABHD17 depalmitoylase family with an IC50 of 0.21 µM against ABHD17B. It blocks N-Ras signaling and suppresses the growth of NRAS-mutant acute myeloid leukemia cells in vitro, making it a valuable tool for studying depalmitoylation and oncogenic Ras pathways.

Research Area

Metabolism Research

Key Properties

• CAS Number: 3007772-60-0
• MW: 627.68
• Formula: C₂₇H₃₆F₃N₇O₅S
• SMILES: C[C@H]1CN(CCN1C(=O)N2C=CC(=N2)S(=O)(=O)N(C)C)CC3=C(C=C(C=C3)C(F)(F)F)N4C5CCC4CN(C5)CC(=O)O
• Target: Others,MAGL

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155803788