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Catalog Number | orb1305597 |
---|---|
Category | Small Molecules |
Description | ABC99 |
CAS Number | 2331255-53-7 |
Purity | 98.65% |
MW | 456.88 |
SMILES | Clc1ccc(CN2CCN3C(C2)C(=O)N(OC(=O)N2CCOc4ccccc24)C3=O)cc1 |
Formula | C22H21ClN4O5 |
Biological Activity | ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |