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AB-423

SKU: orb1296269

Description

AB-423

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number1572510-80-5
MW386.39
Purity99.94% (May vary between batches)
FormulaC17H17F3N2O3S
SMILESCC[C@@H](C)NS(=O)(=O)c1ccc(F)c(c1)C(=O)Nc1ccc(F)c(F)c1
TargetHBV
SolubilityDMSO:60 mg/mL (155.28 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.18 mM)

Bioactivity

In Vitro
AB-423 shows an inhibitory effect on relaxed circular DNA production in AML12-HBV10 and HepDE19 cells (EC50s: ~0.260 μM). AB-423 also suppresses cccDNA formation-dependent HBeAg production in the HepBHAe82 assay (EC50: 0.267 μM) and inhibits HBV DNA levels in culture supernatants of HepG 2.2.15 cells (EC50: 0.134 μM).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, Hepatitis B virus, HBV, AB 423, AB423, AB-423

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 100.00
25 mg
$ 160.00
50 mg
$ 210.00
DispatchUsually dispatched within 5-10 working days
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