AA-CW236

SKU: orb1701311

Description

AA-CW236 is a small molecule that covalently inactivates the DNA repair protein MGMT (O⁶-alkylguanine-DNA alkyltransferase). This inhibitor is utilized in research to sensitize cancer cells to alkylating chemotherapeutics in both cellular and animal models, exploring strategies to overcome treatment resistance.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 1869921-96-9
• MW: 400.78
• Formula: C₁₇H₁₆ClF₃N₄O₂
• SMILES: C(Cl)C1=C(N=NN1CCC=2C(C)=NOC2C)C3=CC=C(OC(F)(F)F)C=C3
• Target: Others,DNA Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132470893