A6770

SKU: orb1693402

Description

A6770 is a potent and selective inhibitor of sphingosine-1-phosphate (S1P) lyase, demonstrated by its ability to induce accumulation of the substrate [³H]dhS1P in IT-79MTNC3 cells (EC₅₀ < 0.01 µM). This effect is attenuated by vitamin B6, confirming target engagement. This tool compound is used in vitro to study S1P metabolism, signaling, and related pathways in immunology and cancer research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1331754-16-5
• MW: 140.142
• Formula: C₆H₈N₂O₂
• SMILES: CC(=O)c1ncc(CO)[nH]1
• Target: LPL Receptor,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53358898