A2AAR/HDAC-IN-1

SKU: orb1687523

Description

A2AAR/HDAC-IN-1 (14c) is a balanced dual antagonist of the A2A adenosine receptor (Ki = 163.5 nM) and inhibitor of histone deacetylase 1 (IC50 = 145.3 nM). This orally bioavailable compound is a research tool for investigating cancer immunotherapy and neurodegenerative diseases in both cellular and animal models.

Research Area

Epigenetics & Chromatin, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2767560-51-8
• MW: 439.47
• Formula: C₂₄H₂₁N₇O₂
• SMILES: C(CC1=CC=C(C(NC2=C(N)C=CC=C2)=O)C=C1)N3C=4C(=C(N=C(N)N4)C5=CC=CO5)C=N3
• Target: HDAC,Others,Adenosine Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165412579