A 83-01 sodium salt

SKU: orb1710343

Description

A 83-01 sodium salt is a potent and selective inhibitor of the TGF-β receptor kinases ALK5, ALK4, and ALK7, with respective IC50 values of 12 nM, 45 nM, and 7.5 nM in transcription assays. This compound is widely used in vitro to study TGF-β/Smad signaling pathways in cancer, fibrosis, and stem cell biology research.

Research Area

Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2828431-89-4
• MW: 444.51
• Formula: C₂₅H₁₉N₅NaS+
• SMILES: S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5.[Na+]
• Target: TGF-beta/Smad,ALK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

133053565