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Description

A 779 is a potent and selective antagonist of the Mas receptor, the G-protein-coupled receptor for angiotensin-(1-7). This tool compound is widely used in cardiovascular and renal research to investigate the distinct physiological roles of the Ang-(1-7)/Mas axis, both in vitro and in vivo.

Research Area

Metabolism Research

Images & Validation

Key Properties

TargetRAAS
CAS Number159432-28-7
MW872.97
FormulaC39H60N12O11
SMILES[H][C@](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](C)C(O)=O

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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A 779 (orb1685465)

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