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A-77636
Catalog Number: orb1944491
| Catalog Number | orb1944491 |
|---|---|
| Category | Small Molecules |
| Description | A-77636 is a potent, selective, and long-acting oral dopamine D1 receptor agonist with an effective concentration (EC50) of 1.1 nM and a corresponding pEC50 value of 8.13. It demonstrates the highest affinity for the dopamine D1 receptor with a dissociation constant (Ki) of 39.8 nM and a pKi of 7.40 ± 0.09. Notably, A-77636 exhibits antiparkinsonian activity [1]. |
| Purity | 98.00% |
| MW | 329.43 |
| Biological Activity | A-77636 is a potent, selective, and long-acting oral dopamine D1 receptor agonist with an effective concentration (EC50) of 1.1 nM and a corresponding pEC50 value of 8.13. It demonstrates the highest affinity for the dopamine D1 receptor with a dissociation constant (Ki) of 39.8 nM and a pKi of 7.40 ± 0.09. Notably, A-77636 exhibits antiparkinsonian activity [1]. |
| CAS Number | 778546-51-3 |
| Formula | C20H27NO3 |
| SMILES | C(N)[C@@H]1O[C@H]([C@]23CC4(CC(C2)(CC(C3)(C4)[H])[H])[H])CC=5C1=CC=C(O)C5O |
| Storage | -20°C |
| Note | For research use only |
A 77636 hydrochloride [orb1306202]
99.62%
145307-34-2
365.89
C20H28ClNO3
1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 1 ml x 10 mM (in DMSO)
