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A 410099.1

SKU: orb1693356

Description

A 410099.1 is a potent inhibitor of BIRC proteins (BIRC2/3/4/7/8) with EC50 values ranging from 4.6 to 93.9 nM. This small molecule is a valuable chemical tool for studying E3 ubiquitin ligase function and serves as a starting point for PROTAC development in cancer research.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number762274-58-8
MW505.1
Purity99.53% (May vary between batches)
FormulaC27H41ClN4O3
SMILESCl.CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCCc2ccccc12 |@:9|
TargetIAP
SolubilityDMSO:40 mg/mL (79.19 mM)

Bioactivity

Target IC50
BIRC3:9.2 nM (EC50)|BIRC7:19.9 nM (EC50)|BIRC2:4.6 nM (EC50)|BIRC4:15.6 nM ( EC50)|BIRC8:93.9 nM (EC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

A 410099.1, A410099.1

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 140.00
5 mg
$ 290.00
10 mg
$ 430.00
25 mg
$ 680.00
50 mg
$ 940.00
100 mg
$ 1,230.00
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