A-1248767

SKU: orb2663629

Description

A-1248767, a derivative of A-1210477, is an MCL-1 inhibitor (IC50=23.9 nM; Ki=0.41 nM) known for its anticancer properties. It binds to MCL-1 with high affinity, induces an increase in MCL-1 protein levels inside cells, and promotes apoptosis in tumor cells.

Research Area

Cell Biology

Key Properties

• CAS Number: 2228052-38-6
• MW: 813.98
• Formula: C₄₇H₅₅N₇O₆
• SMILES: O=C(O)C1=C(C=2C=CC=C(C=3C(=NN(C3C)C)COC4=CC=C(C=C4)N5CCN(C(=O)N(C)C)CC5)C2N1CCN6CCOCC6)CCCOC7=CC=CC=8C=CC=CC78
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

134576153