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Catalog Number | orb2663629 |
---|---|
Category | Small Molecules |
Description | A-1248767, a derivative of A-1210477, is an MCL-1 inhibitor (IC50=23.9 nM; Ki=0.41 nM) known for its anticancer properties. It binds to MCL-1 with high affinity, induces an increase in MCL-1 protein levels inside cells, and promotes apoptosis in tumor cells. |
CAS Number | 2228052-38-6 |
Purity | 98.00% |
MW | 813.98 |
SMILES | O=C(O)C1=C(C=2C=CC=C(C=3C(=NN(C3C)C)COC4=CC=C(C=C4)N5CCN(C(=O)N(C)C)CC5)C2N1CCN6CCOCC6)CCCOC7=CC=CC=8C=CC=CC78 |
Formula | C47H55N7O6 |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |