A-1208746

SKU: orb2663673

Description

A-1208746 is a potent, selective MCL-1 inhibitor (Ki = 0.454 nM) that induces apoptosis via caspase-3/7 activation and loss of mitochondrial membrane potential in vitro. It demonstrates synergistic activity with Navitoclax, supporting its application in oncology research for studying hematological and solid tumor models.

Research Area

Cell Biology

Key Properties

• CAS Number: 1668553-23-8
• MW: 821
• Formula: C₄₅H₅₂N₆O₇S
• SMILES: O=C(O)C1=C(C=2C=CC=C(C=3C(=NN(C3COC4=CC=C(C=C4)N5CCN(CC5)S(=O)(=O)C)C)C)C2N1CCN6CCOCC6)CCCOC7=CC=CC=8C=CC=CC78
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

118734957