A-1155905

SKU: orb2665558

Description

A-1155905 is a potent and selective MCL-1 inhibitor with an IC50 of 33.5 nM and a Ki of 0.58 nM. It disrupts the MCL-1/Bim interaction, inducing caspase-dependent apoptosis in MCL-1-dependent cancer cells in vitro, making it a valuable tool for oncology research targeting apoptotic pathways.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 2228052-37-5
• MW: 802.93
• Formula: C₄₆H₅₁FN₆O₆
• SMILES: O=C(O)C1=C(C=2C=CC=C(C=3C(=NN(C3COC4=CC=C(C=C4)N5CCN(C(=O)C)CC5)C)C)C2N1CCN6CCOCC6)CCCOC7=CC=CC=8C(F)=CC=CC78
• Target: Caspase,Bcl-2 Family,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172638551