A-1155463

• Catalog Number: orb1300502
• Category: Small Molecules
• Description: A-1155463
• CAS Number: 1235034-55-5
• Purity: 99%
• MW: 669.79
• SMILES: C(NC1=NC=2C(S1)=CC=CC2)(=O)C3=C4C(CCN(C4)C5=NC(C(O)=O)=C(CCCOC6=C(F)C=C(C#CCN(C)C)C=C6)S5)=CC=C3
• Formula: C₃₅H₃₂FN₅O₄S₂
• Biological Activity: A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and > 1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM).
• Note: For research use only
• Expiration Date: 12 months from date of receipt.