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(9R)-Exatecan

SKU: orb3181501

Description

(9R)-Exatecan (DX8951f) is the (1R,9S) stereoisomer of Exatecan. Exatecan (DX-8951) functions as a DNA topoisomerase I (topoisomeraseI) inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and is utilized in cancer research.

Research Area

Molecular Biology

Images & Validation

Key Properties

CAS Number2489613-17-2
MW435.46
FormulaC24H22FN3O4
SMILESN[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
TargetADC Cytotoxin,Topoisomerase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information