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8012–3246

SKU: orb3175050

Description

8012-3246 is a selective PLK2 inhibitor with an IC50 value of 774.5 nM. It inhibits the phosphorylation of GSK3β and exhibits significant anticancer activity against colorectal cancer.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number421586-94-9
MW347.33
FormulaC18H13N5O3
SMILESN#CC1=C(OC=2NN=C(C=3C=CN=CC3)C2C1C4=CC=C(O)C(O)=C4)N
TargetPLK,GSK-3

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information