8-Prenylkaempferol

SKU: orb1684796

Description

8-Prenylkaempferol is a small molecule that inhibits pro-inflammatory NO production and suppresses influenza A virus-induced RANTES. Its anti-inflammatory mechanism involves blocking PI3K-mediated NF-κB and IRF-3 activation and partially inhibiting IκB degradation, thereby reducing NF-κB nuclear translocation. This compound is used in research on viral inflammation and innate immune signaling pathways in vitro.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 28610-31-3
• MW: 354.35
• Formula: C₂₀H₁₈O₆
• SMILES: CC(C)=CCc(c(OC(c(cc1)ccc1O)=C1O)c(c(O)c2)C1=O)c2O
• Target: Wnt/beta-catenin,p38 MAPK,PI3K,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5318624