8-Geranyloxypsoralen

SKU: orb1297475

Description

8-Geranyloxypsoralen

Research Area

Infectious Disease & Virology, Metabolism Research, Neuroscience

Key Properties

• CAS Number: 7437-55-0
• MW: 338.40
• Purity: 99.87%
• Formula: C₂₁H₂₂O₄
• SMILES: CC(C)=CCC\C(C)=C\COc1c2occc2cc2ccc(=O)oc12
• Target: BACE,Cytochromes P450,Anti-infection
• Solubility: 10% DMSO+90% Corn Oil:2.00 mg/mL (5.91 mM);DMSO:45.00 mg/mL (132.98 mM)

Bioactivity

• Target IC50:
  CYP3A4:3.93 μM IC50
• In Vitro:
  Through bioassay-guided fractionations, three coumarins were obtained fro the extract of H. andicans and determined to be 8-Geranyloxypsoralen (1), imperatorin (2), and heraclenin (3) based on spectra data. All three compounds possessed nematicidal activities agains the two tested nematodes the median lethal concentration (LC(50)) of compounds 1-3 at 72 h were 188.3, 161.7, and 114.7 mg L(-1) respectively against B. xylophilus and were 117.5, 179.0, and 148.7 mg L(-1) respectively against P. redivivu

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

CYPs, Cytochrome P450, BACE, Antifection, Anti-infection, Antiinfection, 8 Geranyloxypsoralen, 8Geranyloxypsoralen, 8-Geranyloxypsoralen, inhibit, Inhibitor, P450

Compound Identifiers

PubChem CID

5317564