8-Epiloganin

SKU: orb2299343

Description

8-Epiloganin is a bioactive iridoid glycoside isolated from Pedicularis lasiophrys. It demonstrates anti-inflammatory properties by suppressing LPS-induced pro-inflammatory cytokine release, making it a candidate for research in inflammation-related diseases using in vitro cellular models.

Key Properties

• CAS Number: 79172-04-6
• MW: 390.4
• Formula: C₁₇H₂₆O₁₀
• SMILES: O([C@H]1[C@]2([C@@](C(C(OC)=O)=CO1)(C[C@H](O)[C@H]2C)[H])[H])[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O
• Target: Others

Bioactivity

• In Vivo:
  8-Epiloganin showed anti-fatigue activity in mice.
• In Vitro:
  8-Epiloganin(25-200 μM,12h) inhibited the expression of COX-2 and iNOS in RAW264.7 macrophages induced by LPS, thereby inhibiting the production of COX-2-derived PGE2 and iNOS derived NO.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

8-epi-Loganin

Compound Identifiers

PubChem CID

10548420