8-Chloroadenosine-5'-triphosphate sodium

SKU: orb2276834

Description

8-Chloro ATP is a bioactive metabolite of the anticancer agent 8-chloro cAMP. It accumulates in cells, depleting endogenous ATP and inhibiting RNA synthesis and topoisomerase IIα activity, as demonstrated in studies using human multiple myeloma and K562 leukemia cell lines.

Research Area

Molecular Biology

Key Properties

• CAS Number: 793671-47-3
• MW: 629.55
• Formula: C₁₀H₁₁ClN₅O₁₃P₃.4Na
• SMILES: O[C@@H]1[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@@H](N2C3=NC=NC(N)=C3N=C2Cl)[C@@H]1O.[Na+].[Na+].[Na+].[Na+]
• Target: Topoisomerase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

56846240