7,8-Didehydrocimigenol

SKU: orb1683343

Description

7,8-Didehydrocimigenol is a research compound with potential applications in cardiovascular disease research, particularly atherosclerosis. It functions by upregulating PPAR-γ and suppressing TNF-α-induced NF-κB activity in endothelial cells, leading to the selective downregulation of VCAM-1 expression. This mechanism has been investigated in vitro for its anti-inflammatory effects on the endothelium.

Research Area

Cell Biology, Metabolism Research, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 150972-72-8
• MW: 486.693
• Formula: C₃₀H₄₆O₅
• SMILES: [H][C@]12[C@H](C)C[C@H]3O[C@@]1(O[C@@H]3C(C)(C)O)[C@H](O)[C@@]1(C)C3=CC[C@]4([H])[C@]5(C[C@@]35CC[C@]21C)CC[C@H](O)C4(C)C |t:20|
• Target: PPAR,IκB/IKK,Akt,TNF,ERK,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

101577840