6H05 (TFA)

SKU: orb1299917

Description

6H05 TFA is a selective, allosteric inhibitor targeting the oncogenic K-Ras(G12C) mutant. It is a valuable chemical probe for investigating Ras-driven tumor biology in both cellular and animal models, supporting research in oncology and targeted cancer therapy development.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2061344-88-3
• MW: 590.14
• Purity: 98.83% (May vary between batches)
• Formula: C₂₂H₃₁ClF₃N₃O₄S₃
• SMILES: OC(=O)C(F)(F)F.CN(C)CCSSCCNC(=O)C1CCN(CC1)C(=O)CSc1ccc(Cl)cc1
• Target: Ras,Kras
• Solubility: DMSO:51 mg/mL (86.42 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ras, Inhibitor, KRAS G12C, inhibit, 6H05, 6H05 (TFA), 6H-05 (TFA), 6H05 TFA, 6H05 Trifluoroacetate, 6H05 trifluoroacetate

Compound Identifiers

PubChem CID

86208069