673-A

• Catalog Number: orb1737496
• Category: Small Molecules
• Description: 673-A
• CAS Number: 109437-62-9
• Purity: 0.98
• MW: 223.27
• SMILES: C(=O)C1=CC=C(N2CC=3C(C2)=CC=CC3)C=C1
• Formula: C₁₅H₁₃NO
• Biological Activity: 673-A is an aldehyde dehydrogenase (ALDH1A) inhibitor that depletes CD133+ cancer stem cells (CSC) in ovarian cancer cell lines. 673-A triggers necroptosis in ovarian CSCs and induces expression of mitochondrial uncoupling proteins (UCP). 673-A also overcomes chemotherapy resistance in vivo.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.