6,6′-Trehalose Dioleate

SKU: orb2815789

Description

6,6′-Trehalose dioleate (6,6′-TDO) is a glycolipid excipient for mRNA encapsulation in lipid nanoparticles (LNPs), enhancing immunogenicity in vaccine research. In vivo studies show it promotes a Th1/Th2 antibody response (IgG2a/IgG1) without inducing significant hepatotoxicity or renal markers in mice, supporting its use for safer nucleic acid delivery platforms.

Key Properties

• CAS Number: 338733-40-7
• MW: 871.19
• Formula: C₄₈H₈₆O₁₃
• SMILES: O([C@H]1O[C@H](COC(CCCCCCC/C=C\CCCCCCCC)=O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]2O[C@H](COC(CCCCCCC/C=C\CCCCCCCC)=O)[C@@H](O)[C@H](O)[C@H]2O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168736749