6-Thio-GTP

• Catalog Number: orb1734185
• Category: Tools
• Description: 6-Thio-GTP
• CAS Number: 17670-19-8
• Concentration: 10 mM-11 mM
• Form/Appearance: solution in water; Color: colorless to slightly yellow; pH: 7.5 ± 0.5
• Purity: ≥ 95% (HPLC)
• MW: Theoretical MW: 539.24 g/mol (free acid); Detected MW: 538.97 g/mol (free acid)
• SMILES: [C@@H]1([C@H]([C@@H](O[C@@H]1COP(=O)(OP(=O)(OP(=O)(O)O)O)O)n1c2c(nc1)c(nc(n2)N)S)O)O
• Formula: C₁₀H₁₆N₅O₁₃P₃S
• Storage: store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible
• Note: For research use only
• Application notes: Allosteric effect on E.coli CTP-synthase; Inhibition of Vac-1-Rac signalling; Immunosuppression by blockade of GTPase activation; Immunosuppressive drug (transplantation, inflammation). ; Spectroscopic Propertie: λmax 257 nm, ε 8.8 L mmol-1 cm-1 (Tris-HCl, pH 7.5), λmax 342 nm, ε 24.8 L mmol-1 cm-1 (Tris-HCl pH 7.5).
• Expiration Date: 12 months from date of receipt.