6-Hydroxycoumarin

SKU: orb1304704

Description

6-Hydroxycoumarin is a small molecule inhibitor of carbonic anhydrases CA9 and CA12. It demonstrates cytotoxic activity in vitro against human cancer cell lines, including HL60, HCT116, and COLO205, with IC50 values ranging from 35 to 42 µM. This compound is used in biochemical research to study tumor metabolism and hypoxia-related pathways.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 6093-68-1
• MW: 162.14
• Purity: 98.65% (May vary between batches)
• Formula: C₉H₆O₃
• SMILES: Oc1ccc2oc(=O)ccc2c1
• Target: Carbonic Anhydrase,Antibacterial,Antifungal
• Solubility: DMSO:20 mg/mL (123.35 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (30.84 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, CA12, CA9, 6 Hydroxycoumarin, 6-hydroxychromen-2-one, 6Hydroxycoumarin, 6-Hydroxycoumarin, Carbonic Anhydrase, CarbonicAnhydrase

Compound Identifiers

PubChem CID

99477