6-Biopterin

SKU: orb1299675

Description

6-Biopterin

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 22150-76-1
• MW: 237.22
• Purity: 99.11%
• Formula: C₉H₁₁N₅O₃
• SMILES: C[C@H](O)[C@H](O)c1cnc2nc(N)nc(O)c2n1
• Target: Endogenous Metabolite,NO Synthase,NOD
• Solubility: DMSO:6 mg/mL (25.29 mM)

Bioactivity

• In Vitro:
  The oxidized cofactor 6-biopterin (0.2 x 10(-6) M) is extremely cytotoxic to human melanocytes under in vitro conditions. Consequently, its reduction to 6-BH4 via q-BH2 is essential to melanocyte viability.human thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione.

Storage & Handling

• Storage: store at low temperature,store under nitrogen | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Endogenous Metabolite, EndogenousMetabolite, Inhibitor, L-Biopterin, NOSynthase, NOS, inhibit, Nitric oxide synthases, NO synthesis, NO Synthase, 6Biopterin, 6-Biopterin, 6 Biopterin

Compound Identifiers

PubChem CID

135403659