5-Methyl cromolyn disodium

SKU: orb3136566

Description

5-Methyl cromolyn (C5OH) disodium is a cromolyn analog that acts as an S100P inhibitor. It prevents the interaction between S100P and its receptor RAGE, hinders NF-κB activity and cell proliferation, and enhances apoptosis induced by Gemcitabine. In murine models with PDAC, 5-Methyl cromolyn disodium reduces tumor growth and metastasis, thereby extending survival. This compound is suitable for pancreatic cancer research, including studies on pancreatic ductal adenocarcinoma (PDAC).

Key Properties

• CAS Number: 1221154-42-2
• MW: 540.38
• Formula: C₂₅H₁₈Na₂O₁₁
• SMILES: O=C(C(OC1=CC=CC(OCCC(CCOC(C=CC=C2OC(C([O-])=O)=C3)=C2C3=O)O)=C14)=CC4=O)[O-].[Na+].[Na+]
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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