5-LOX inhibitor

SKU: orb1962274

Description

This compound, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one, is a 5-lipoxygenase (5-LOX) inhibitor identified as a process-related impurity of itraconazole. It serves as a research tool for investigating the 5-LOX pathway in leukotriene biosynthesis during in vitro enzymatic and cellular assays.

Research Area

Metabolism Research, Metabolism Research; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 106461-41-0
• MW: 393.48
• Purity: 98.01% (May vary between batches)
• Formula: C₂₂H₂₇N₅O₂
• SMILES: CCC(C)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(O)cc2)c1=O
• Target: Hedgehog/Smoothened,Lipoxygenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5-LOX, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one

Compound Identifiers

PubChem CID

4445081