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5-LOX inhibitor

SKU: orb1962274

Description

This compound, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one, is a 5-lipoxygenase (5-LOX) inhibitor identified as a process-related impurity of itraconazole. It serves as a research tool for investigating the 5-LOX pathway in leukotriene biosynthesis during in vitro enzymatic and cellular assays.

Research Area

Metabolism Research, Metabolism Research; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number106461-41-0
MW393.4821
Purity98.52% (May vary between batches)
FormulaC22H27N5O2
SMILESCCC(C)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(O)C=C1
TargetLipoxygenase,Hedgehog/Smoothened

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

5-LOX, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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5 mg
$ 80.00
10 mg
$ 100.00
25 mg
$ 130.00
50 mg
$ 170.00
100 mg
$ 230.00
500 mg
$ 520.00
DispatchUsually dispatched within 5-10 working days
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