5-Hydroxy-1-methylhydantoin

SKU: orb1304974

Description

5-Hydroxy-1-methylhydantoin (HD-003) is a creatinine-derived antioxidant and hydroxyl radical scavenger studied for renal and vascular protection. Research indicates it suppresses high glucose-induced B2KR expression and attenuates bradykinin-driven MAPK/CTGF signaling in VSMCs, demonstrating potential in models of diabetic nephropathy and vascular remodeling.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 84210-26-4
• MW: 130.1
• Purity: 99.99% (May vary between batches)
• Formula: C₄H₆N₂O₃
• SMILES: OC1N(C)C(=O)NC1=O
• Target: Bradykinin Receptor,ROS,Reactive Oxygen Species
• Solubility: DMSO:60 mg/mL (461.18 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5 Hydroxy 1 methylhydantoin, 5Hydroxy1methylhydantoin, 5-Hydroxy-1-methylhydantoin, Bradykinin Receptor, BradykininReceptor, bradykinin B2, HD 003, HD003, HD-003, NZ 419, NZ419, NZ-419

Compound Identifiers

PubChem CID

3036247