5α-Androstan-3α-ol

SKU: orb3135298

Description

5α-Androstan-3α-ol is a γ-aminobutyric acid (GABA) receptor agonist. It inhibits the transcriptional activity of the orphan nuclear receptor CAR (constitutive androstane receptor). By binding to CAR and promoting its dissociation from coactivator proteins, 5α-Androstan-3α-ol negatively regulates CAR's activity. This compound is useful for studying hormone metabolism and drug detoxification mechanisms mediated by nuclear receptors.

Key Properties

• CAS Number: 7657-50-3
• MW: 276.46
• Formula: C₁₉H₃₂O
• SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)CCC4)[H])(CC[C@]1(C[C@H](O)CC2)[H])[H])[H]
• Target: GABA Receptor,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GABA Receptor,Others