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5-(2-Chloroacetamide) thalidomide

SKU: orb3028715

Description

5-(2-Chloroacetamide) thalidomide is an analog of Thalidomide. Thalidomide functions by recruiting E3 ligase for ubiquitination, leading to the degradation of specific proteins. This compound features a chloroacetamide moiety, which acts as a thiol-specific reactive group.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1957235-51-6
MW349.726
FormulaC15H12ClN3O5
SMILESO=C(NC1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3)CCl
TargetLigands for E3 Ligase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information