4beta-Hydroxywithanolide E

SKU: orb1683481

Description

4β-Hydroxywithanolide E (4bHWE) is a natural compound with demonstrated anti-tumor and anti-inflammatory properties. It inhibits colon cancer cell and spheroid growth by modulating splicing factors and histone modifications, while in vivo studies show it attenuates diabetes progression by suppressing NF-κB signaling in adipose tissue.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 54334-04-2
• MW: 502.604
• Formula: C₂₈H₃₈O₈
• SMILES: [H][C@@]12C[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3(O)CC[C@@]4(O)[C@@](C)(O)[C@@]3([H])CC(C)=C(C)C(=O)O3)[C@@]3(C)C(=O)C=C[C@H](O)[C@@]13O2 |c:37,t:26|
• Target: COX|||HSP|||NF-κB|||PARP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

73621