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4A3-SC10

SKU: orb3178014

Description

4A3-SC10 is an ionizable cationic lipid (pKa = 6.57) utilized in the formation of lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. In mice, these LNPs, which contain 4A3-SC10, preferentially accumulate in the liver, kidney, and spleen. Furthermore, LNPs with 4A3-SC10 that encapsulate an mRNA reporter stimulate reporter expression in 4T1 breast cancer cells, B16/F10 melanoma cells, and AML12 hepatocytes.

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Key Properties

TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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