4',5-Dihydroxyflavone

SKU: orb1299083

Description

4',5-Dihydroxyflavone is a bioactive flavonoid that acts as an inhibitor of soybean lipoxygenase-1 (LOX-1, Ki: 102.6 µM) and yeast α-glucosidase (IC50: 66 µM). This compound is utilized in biochemical research to study enzyme kinetics, metabolic pathways, and potential therapeutic applications in vitro.

Research Area

Metabolism Research

Key Properties

• CAS Number: 6665-67-4
• MW: 254.24
• Purity: 99.81% (May vary between batches)
• Formula: C₁₅H₁₀O₄
• SMILES: Oc1ccc(cc1)-c1cc(=O)c2c(O)cccc2o1
• Target: glycosidase,Glucosidase,Lipoxygenase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.73 mM);DMSO:155 mg/mL (609.66 mM)

Bioactivity

• Target IC50:
  LOX1:Ki: 102.6 μM|α-glucosidase:66 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

4',5Dihydroxyflavone, 4',5-Dihydroxyflavone, 4',5 Dihydroxyflavone, Glucosidase, Inhibitor, inhibit, Lipoxygenase, LOX, LOX-1, α-glucosidase

Compound Identifiers

PubChem CID

165521