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4,5-Dehydro-6-oxoallosecurinine

SKU: orb3210863

Description

4,5-Dehydro-6-oxoallosecurinine is an activator of the Keap1-Nrf2 pathway. It facilitates the nuclear translocation of Keap1-Nrf2, inducing the expression of antioxidant and cytoprotective genes. This compound reduces nitric oxide (NO) production and decreases the levels of iNOS, TNF-α, IL-6, and IL-1β in LPS-stimulated microglial cells. 4,5-Dehydro-6-oxoallosecurinine is applicable in the research of neurodegenerative diseases.

Images & Validation

Key Properties

TargetInterleukin,Nrf2,TNF,NO Synthase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information