4,4′-Secalonic acid D

SKU: orb2943046

Description

4,4′-Secalonic acid D is a potent PARP1 inhibitor that induces tumor cell death through apoptosis and pyroptosis by promoting ROS accumulation, DNA damage, and caspase-3/GSDME pathway activation. This small molecule is a valuable research tool for studying cancer cell death mechanisms in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 2265910-52-7
• MW: 638.572
• Formula: C₃₂H₃₀O₁₄
• SMILES: C(OC)(=O)[C@]12C(C(=O)C=3C(O1)=C(C=CC3O)C4=C5C(C(=O)C=6[C@@](C(OC)=O)(O5)[C@H](O)[C@@H](C)CC6O)=C(O)C=C4)=C(O)C[C@H](C)[C@H]2O
• Target: Pyroptosis,Caspase,Reactive Oxygen Species,PARP,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

12309483