4'-O-Methylochnaflavone

SKU: orb2813877

Description

4'-O-Methylochnaflavone is a biflavonoid isolated from Ginkgo biloba leaves, known to suppress Con A- and LPS-induced lymphocyte proliferation. This compound is utilized in immunology research to study anti-inflammatory and immunomodulatory mechanisms in vitro.

Key Properties

• CAS Number: 49619-87-6
• MW: 552.48
• Purity: 99.49% (May vary between batches)
• Formula: C₃₁H₂₀O₁₀
• SMILES: O=C1C=C(OC=2C=C(O)C=C(O)C12)C=3C=CC(OC=4C=C(C=CC4OC)C=5OC=6C=C(O)C=C(O)C6C(=O)C5)=CC3
• Target: Others
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• Target IC50:
  PIM3:11.84 μM
• In Vitro:
  4'-O-Methylochnaflavone treatment significantly increased the content of nitric oxide in rat spongy endothelial cells (RCECs), and had a significant repair effect on PA-stimulated endothelial dysfunction. 4'-O-Methylochnaflavone inhibits PIM3 with an IC50 value of 11.84 μM.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

4' O Methylochnaflavone, 4'OMethylochnaflavone, 4'-O-Methylochnaflavone

Compound Identifiers

PubChem CID

5384799