4'-O-Methylglabridin

SKU: orb3211767

Description

4'-O-Methylglabridin is an apoptosis (apoptosis) inducer with antioxidant, cell cycle interference, and anticancer cytotoxic properties. It effectively inhibits various cancer cell lines, including liver, breast, and colorectal cancers. This compound promotes cell accumulation in subG1 and G2/M phases by reducing phosphorylation of Rb (Ser807/811) and p21 protein expression. It triggers caspase-dependent apoptosis through cytochrome C release and Caspase-9 activation. Additionally, 4'-O-Methylglabridin exhibits antioxidant effects by inhibiting lipid peroxidation levels and decreasing β-carotene consumption, thereby preventing LDL oxidation. It is useful in research related to various cancers and atherosclerotic diseases.

Key Properties

• CAS Number: 68978-09-6
• MW: 338.40
• Formula: C₂₁H₂₂O₄
• SMILES: CC1(C)OC2=C(C3=C(C[C@@H](CO3)C4=C(O)C=C(OC)C=C4)C=C2)C=C1
• Target: Caspase,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase,Apoptosis