4-O-Methyl-ascochlorin

SKU: orb3179787

Description

4-O-Methyl-ascochlorin (Compound MAC) is a derivative of Ascochlorin that selectively induces apoptosis and G1 phase arrest in K562 leukemia cells while downregulating c-Myc expression. It enhances the phosphorylation of AMPK and inhibits the phosphorylation of mTOR and its target proteins [including p70S6 K and 4E-BP-1]. 4-O-Methyl-ascochlorin is useful for leukemia research.

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Key Properties

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CAS Number	38561-40-9
MW	418.96
Formula	C₂₄H₃₁ClO₄
SMILES	C(/C=C(/C=C/[C@]1(C)[C@@H](C)C(=O)CC[C@H]1C)\C)C2=C(OC)C(Cl)=C(C)C(C=O)=C2O
Target	mTOR,c-Myc,Apoptosis,AMPK

Storage & Handling

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Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

mTOR,c-Myc,Apoptosis,AMPK

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