4-Hydroxyflavanone

SKU: orb1299318

Description

4-Hydroxyflavanone is a natural flavonoid with demonstrated vasorelaxant properties. It is used in cardiovascular research to study vascular tone mechanisms in vitro and has shown bioactivity in models of hypertension.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 6515-37-3
• MW: 240.25
• Purity: 99.34% (May vary between batches)
• Formula: C₁₅H₁₂O₃
• SMILES: Oc1ccc(cc1)C1CC(=O)c2ccccc2O1
• Target: NO Synthase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.32 mM);DMSO:12 mg/mL (49.95 mM)

Bioactivity

• In Vitro:
  4'-hydroxyflavanone were evaluated for the inhibition of nitric oxide production in lipopolysaccharide (LPS)-stimulated product of nitrite in RAW 264.7 cells with IC50 values of 15.72.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NOSynthase, lipid synthesis, Inhibitor, inhibit, NO Synthase, nitric oxide, hepatic steatosis, dyslipidemia, 4Hydroxyflavanone, 4'-Hydroxyflavanone, 4-Hydroxyflavanone, 4 Hydroxyflavanone, synthetic analogue, SREBP maturation

Compound Identifiers

PubChem CID

165506