4-Hydroxyantipyrine

SKU: orb1225980

Description

Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (In Vitro):4-Hydroxyantipyrine increase the tissue-to-plasma concentration ratio of Citicoline in the brain and liver and that of thiopental sodium in the brain, liver, and heart.4-Hydroxyantipyrine enhances the blood-brain barrier (BBB) permeability of Antipyrine considering to be concerned with the increase of the Kp value of Antipyrine in the brain.

Key Properties

• CAS Number: 1672-63-5
• MW: 204.23
• Purity: >98% (HPLC)
• Formula: C₁₁H₁₂N₂O₂
• SMILES: CN1N(C(=O)C(O)=C1C)C1=CC=CC=C1
• Target: COX
• Solubility: DMSO: 10 mM

Bioactivity

• In Vitro:
  4-Hydroxyantipyrine increase the tissue-to-plasma concentration ratio of Citicoline in the brain and liver and that of thiopental sodium in the brain, liver, and heart.4-Hydroxyantipyrine enhances the blood-brain barrier (BBB) permeability of Antipyrine considering to be concerned with the increase of the Kp value of Antipyrine in the brain.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

COX